Natriumpicosulfaat

Generic name
Natriumpicosulfaat
Brand name
ATC Code
A06AB08
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Natriumpicosulfaat

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Sodiumpicosulfate is  locally active in the colon and are not absorbed in detectable amounts.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Constipation
  • Oral
    • ≥ 4 years
      [2] [3]
      • 2.5 - 5 mg/day in 1 dose Take in the evening..
        • If the effect is insufficient, the dosage can be increased on a trial basis, dosage average 1 mg per 5 kg body weight, max 10 mg/day
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.
    • 4 years up to 10 years
      • 2.5 - 5 mg/day in 1 dose Take in the evening..
        • If the effect is insufficient, the dosage can be increased on a trial basis, dosage average 1 mg per 5 kg body weight, max 10 mg/day
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.
    • 10 years up to 18 years
      • 5 - 10 mg/day in 1 dose Take in the evening..
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

In children, apply only on the advice of a physician. In children < 4 years of age, sodium picosulfate is less effective, as in these children the intestinal microflora is not yet sufficiently developed.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

DRUGS FOR CONSTIPATION

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Softeners, emollients
A06AA01
Contact laxatives
A06AB02
A06AB06
A06AB06
A06AB58
Bulk-forming laxatives
A06AC01
Osmotically acting laxatives
A06AD12
A06AD11
A06AD65
A06AD65
A06AD15
A06AD65
Enemas
A06AG
A06AG10
A06AG10
A06AG04
A06AG11
A06AG01
Other drugs for constipation
A06AX01
A06AX02

References

  1. M. Groeneweg- kinder MDL arts,, Expert opinie , Correspondentie 08-07-2018
  2. Sanofi, SmPC Laxoberal 7,5mg/ml Tropfen zum Einnehmen_Laxoberal 5mg Tabletten (6926.00.01_6926.00.00), 07/2017
  3. Sanofi, SmPC Laxoberal 2,5mg Weichkapseln (6926.00.04), 03/2007
  4. Opella Healthcare Austria GmbH, SmPC Guttalax 7,5 mg/ml Tropfen (17160), 12/2024

Changes

Therapeutic Drug Monitoring


Overdose