Dextromethorphan

Generic name
Dextromethorphan
Brand name
ATC Code
R05DA09
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Dextromethorphan

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Cough
  • Oral
    • 2 years up to 6 years
      • Dextromethorphan hydrobromide monohydrate. 7.5 - 10 mg/dose, as required 2-3 times daily. Max: 30 mg/day.
    • 6 years up to 12 years
      • Dextromethorphan hydrobromide monohydrate: 7.5 - 15 mg/dose, as required, max. 6x daily. Max: 60 mg/day.
    • 12 years up to 18 years
      • Dextromethorphan hydrobromide monohydrate: 10 - 30 mg/dose, as required, max. 6x daily. Max: 120 mg/day.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Unknown frequency: Dystonia, especially in children [SmPC Silomat® DMP]

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

In children, serious adverse events may occur in the event of an overdose, including neurological disorders. Caregivers should be instructed not to exceed the recommended dose. (SmPC easybronchial STOP JUNIOR)
Chronic cough may be an early symptom of bronchial asthma, therefore dextromethorphan is not indicated for the attenuation of this cough, particularly in children. 
Cases of abuse and dependence on dextromethorphan have been reported. Caution is particularly advised in adolescents and young adults with a history of drug abuse or psychoactive substance use. (SmPC Silomat DMP)

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

HOESTPRIKKELDEMP.MIDD., EXCL COMB.PREP. MET EXPECTORANTIA

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Opium alkaloids and derivatives
R05DA04
R05DA07

References

  1. Qualiphar, SmPC Tussipect (RVG 19939) 9-10-2019, www.geneesmiddeleninformatiebank.nl
  2. STADA Consumer Health Deutschland GmbH, SmPC Silomat® DMP gegen Reizhusten, Lutschpastillen (49060.00.00), 06/2022
  3. Easypharm OTC GmbH, SmPC easybronchial STOP JUNIOR Sirup 1,5 mg/mL (136709), aufgerufen am 21.06.2023, https://aspregister.basg.gv.at/aspregister/faces/aspregister.jspx
  4. Teva B.V., SmPC Tussastopp-Lösung zum Einnehmen (1-27312), aufgerufen am 21.06.2023, https://aspregister.basg.gv.at/aspregister/faces/aspregister.jspx

Changes

Therapeutic Drug Monitoring


Overdose