Crystalloid solutions

Generic name
Crystalloid solutions
Brand name
ATC Code
B05BB01
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Crystalloid solutions

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information is present at this moment.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Fluid resuscitation in burns
  • Intravenous
    • 0 years up to 18 years

      • Initially: 4 ml/kg/day per % of total body surface burned

      • Half the calculated volume is given in the first 8 hours and the other half in the next 16 hours. Monitor the diuresis per hour.

        Combined with a maintenance glucose-salt infusion:
        < 10 kg: 100 ml/kg/24 hours
        for every kg in bodyweight between 10 and 20 kg: +50 ml/kg/24 hours
        for every kg in bodyweight between 20 and 30 kg: +20 ml/kg/24 hours
        Example: a child weighing 25 kg: 1000 ml + 500 ml + 100 ml
Fluid supplementation if the acid-base equilibrium is not disturbed or in mild acidosis, isotonic and hypotonic dehydration, recovery of the intravascular volume as a short-term treatment
  • Intravenous
    • 1 month up to 12 years
      • 20 - 100 ml/kg/day, continuous infusion. Average infusion rate:
        1 month to 1 year: 6-8 ml/kg/hour
        1-2 years: 4-6 ml/kg/hour
        2-11 years: 2-4 ml/kg/hour.
    • ≥ 12 years
      • Up to 40 ml/kg/day, continuous infusion. Infusion rate: max. 5 ml/kg/hour.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Solutions containing lactate should be administered with particular care to neonates younger than 3 months.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

I.V. SOLUTIONS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Solutions affecting the electrolyte balance
B05BB01
B05BB03
Solutions producing osmotic diuresis
B05BC01

References

  1. Maco Pharma, SmPC Ringer Lactaat (RVG 34557) 09-05-2011, www.cbg-meb.nl
  2. NVK, Eerste opvang van brandwondenpatienten (1e 24 uur), www.nvk.nl, 2014
  3. B. Braun Melsungen AG, SmPC Ringerlactaat (RVG 51058) 25-06-2015, www.geneesmiddeleninformatiebank.nl

Changes

Therapeutic Drug Monitoring


Overdose