Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

The liquid formulations can contain alcohol; caution is needed when using them in young children because of the possibility of alcohol intoxication. Allowance should be made in everyday activities for dizziness occurring.
Using bromhexine as a mucolytic is not recommended in children aged under 2 because paradoxical reactions can occur (“filling up”). Mucolytics can obstruct the respiratory tract of children aged under 2 years as a result of the physiological characteristics of the respiratory tract in this age group. The ability to
cough up slime may be limited.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

• RESPIRATORY SYSTEM
• COUGH AND COLD PREPARATIONS

EXPECTORANTIA, EXCL COMB.PREP. MET HOESTPRIKKELDEMP.MIDD.

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

References

1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
2. Boehringer Ingelheim BV, SPC Bisolvon (RVG 20431, 06053), www.cbg-meb.nl, Geraadpleegd 14 november 2012, http://db.cbg-meb.nl/IB-teksten/h06053.pdf

Changes

Therapeutic Drug Monitoring

Overdose