Pyrantel

Generic name
Pyrantel
Brand name
ATC Code
P02CC01
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Pyrantel is only absorbed from the gastrointestinal tract to a small extent [SmPC Helmex].

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Infections with gastrointestinal parasites (Enterobius vermicularis/Oxyuren (pinworm), Ancylostoma duodenale (hookworm))
  • Oral
    • 6 months up to 18 years
      [1] [2]
      • 10 mg/kg/dose, once only. Max: 1 g/dose.

      • Oxyuren: repeat therapy after 2 – 4 weeks
        Other infections:  if necessary repeat therapy after max. 6 months
Infections with Necator americanus (American hookworm)
  • Oral
    • 6 months up to 18 years
      [2]
      • 10 mg/kg/day in 1 dose. Max: 1 g/dose. for 3 days..

      • Alternative: 20 mg/kg/dose, max. 1 g/dose for 2 days

         If necessary repeat therapy after max. 6 months
Infections with Ascaris lumbricoides (roundworm)
  • Oral
    • 6 months up to 18 years
      [1] [2]
      • 5 mg/kg/dose, once only. Max: 1 g/dose.

      • If necessary repeat therapy after max. 6 months

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTINEMATODAL AGENTS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Benzimidazole derivatives
P02CA03
P02CA01
Imidazothiazole derivatives
P02CE01
Avermectines
P02CF01

References

  1. InfectoPharm, SmPC Helmex® 250 mg Kautabletten (6120655.00.00), 05/2020
  2. InfectoPharm, SmPC Helmex® 250 mg/5 ml Suspension zum Einnehmen (7289.00.00), 05/2020

Changes

Therapeutic Drug Monitoring


Overdose