Terbinafine, cutaneous

Generic name
Terbinafine, cutaneous
Brand name
ATC Code
D01AE15
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Terbinafine, cutaneous

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Pharmacokinetic parameters have not been studied in children aged less than 12 years; in adults and children of ≥ 12 years, it has been reported that less than 5% of the dose is absorbed.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Fungal infections of the skin
  • Cutaneous
    • 1 month up to 18 years
      [1] [3]

      • Apply 1% cream once or twice daily to the affected skin

      • Duration of treatment:

        For 1-4 weeks

      • Only limited studies have been carried out into the use of terbinafine in children.

         

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Itching, erythema, burning sensation, contact dermatitis

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTIFUNGALS FOR TOPICAL USE

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Imidazole and triazole derivatives
D01AC02
Other antifungals for topical use
D01AE13
IMIDAZOLE AND TRIAZOLE DERIVATIVES
D01AC02
OTHER ANTIFUNGALS FOR TOPICAL USE
D01AE13

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. GlaxoSmithKline Consumer Healthcare B.V., SPC Lamisil creme (RVG 14843) 7-01-2016, www.geneesmiddeleninformatiebank.nl
  3. NHG, Standaard Dermatomycosen , 2008 (feb), http://nhg.artsennet.nl/kenniscentrum/k_richtlijnen/k_nhgstandaarden/Samenvattingskaartje-NHGStandaard/M64_svk.htm

Changes

Therapeutic Drug Monitoring


Overdose