Pembrolizumab

Generic name
Pembrolizumab
Brand name
ATC Code
L01XC18

Pembrolizumab

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information is present at this moment.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Recurrent or refractory Hodgkin lymphoma
  • Intravenous
    • ≥ 3 years
      • 2 mg/kg/dose once every 3 weeks. Max: 200 mg/dose.
      • Directions for administration:

        Infusion in 30 minutes

Melanoma
  • Intravenous
    • ≥ 12 years
      • 2 mg/kg/dose once every 3 weeks. Max: 200 mg/dose.
      • Directions for administration:

        Infusion in 30 minutes

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Reference

  1. Merck Sharp & Dohme B.V., SmPC Keytruda (EU/1/15/1024/001) Rev 47, 26-07-2022, www.ema.europa.eu

Changes

Therapeutic Drug Monitoring


Overdose