Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Insulin, long-acting and short-acting or ultrashort-acting (in combination)

Generic name
Insulin, long-acting and short-acting or ultrashort-acting (in combination)
Brand name
ATC Code
A10AD06

Pharmacokinetics in children

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Diabetes mellitus, insulin-dependent
  • Subcutaneous
    • ≥ 2 years
      [1]
      • Dose depending on the blood sugars.

      • Treatment by or after consulting a paediatric specialist (paediatric endocrinologist) who has experience of using insulins.

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Renal impaiment in children > 3 months

The insulin requirement may be decreased in cases of reduced renal function. The dosage is adjusted depending on the blood glucose measurements in this case.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Be extra careful with the use of this combination preparation in children: severe hypoglycaemia may occur more frequently than with a basal-bolus regime, especially in the age range 2 to 5 years

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Insulins and analogues for injection, fast-acting
A10AB01
A10AB04
Insulins and analogues for injection, intermediate-acting
A10AC01
Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
A10AD01
Insulins and analogues for injection, long-acting
A10AE

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Reference

  1. Novo Nordisk A/S, SmPC Ryzodeg (EU/1/12/806/001-005) 16-11-2017, www.geneesmiddelinformatiebank.nl

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Changes

Changes