- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
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Available formulations
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Dosages
| Acute moderate pain |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications in children
Tonsillectomy and/or adenoidectomy in patients aged 12–18 years.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Codeine is not suitable for children aged < 12 years.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Natural opium alkaloids | ||
|---|---|---|
| N02AA03 | ||
| N02AA01 | ||
| N02AA05 | ||
| Phenylpiperidine derivatives | ||
|---|---|---|
| N02AB03 | ||
| N02AB03 | ||
| N02AB02 | ||
| Diphenylpropylamine derivatives | ||
|---|---|---|
| N02AC06 | ||
| N02AC03 | ||
| Oripavine derivatives | ||
|---|---|---|
| N02AE01 | ||
| Morphinan derivatives | ||
|---|---|---|
| N02AF02 | ||
| Other opioids | ||
|---|---|---|
| N02AX06 | ||
| N02AX01 | ||
| N02AX02 | ||
| Opioids in combination with non-opioid analgesics | ||
|---|---|---|
| N02AJ13 | ||
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Reference
- Pharmachemie B.V., SmPC Paracetamol/codeine (RVG 55665) 17-02-2016, www.geneesmiddeleninformatiebank.nl
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Changes
Changes
