- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Phimosis |
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| Steroid-sensitive dermatoses |
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
The risk of systemic effects is greatest when: used on children, used under occlusion, used on large areas of skin or skin folds, and used simultaneously with penetration-enhancing medicines (such as salicylic acid, urea, propylene glycol).
In children, the secretion of growth hormone can be suppressed. No systemic or local side effects were reported when using clobetasol in phimosis.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Be cautious when using on children (relatively large skin surface area and thin skin), due to the increased risk of systemic side effects. Prolonged use of particularly potent dermatocorticosteroids in children can lead more quickly to adrenal suppression and also to growth hormone suppression; during prolonged use, it is recommended to regularly monitor height and weight and to determine plasma cortisol levels.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Corticosteroids, weak (group I) | ||
|---|---|---|
| D07AA02 | ||
| Corticosteroids, moderately potent (group II) | ||
|---|---|---|
| D07AB01 | ||
| D07AB02 | ||
| D07AB09 | ||
| Corticosteroids, potent (group III) | ||
|---|---|---|
| D07AC01 | ||
| D07AC03 | ||
| D07AC17 | ||
| D07AC14 | ||
| D07AC13 | ||
| D07AC18 | ||
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References
- van Basten JP, et al, [The use of corticosteroid cream to treat phimosis], Ned Tijdschr Geneeskd, 2003, Aug 9;147(32), 1544-7
- GlaxoSmithKline BV, SmPC Dermovate creme RVG 06932 24-5-2018, www.geneesmiddelinformatiebank.nl
- Nederlandse Vereniging voor Dermatologie en Venereologie, Multidisciplinaire evidence-based richtlijn Psoriasis, 2017
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Changes
Changes
