- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
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Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
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Available formulations
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Dosages
| Severe mucositis during chemotherapy and irradiation |
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Chlorhexidine must not be swallowed. In young children aged (< 5 years), apply the fluid using brushes.
Chlorhexidine solution must not be mixed with physiological saline, because that significantly reduces the effect. The drug has a bitter taste and often causes brown discolouration of teeth (incl. molars). The latter effect is amplified by toothpaste that contains fluoride and orally administered antibiotics, in particular amoxicillin suspension. The toothpastes Elmex® and Zendium® do not contain sodium lauryl sulphate and can be used together with chlorhexidine. After the treatment, the discolouration can be removed by polishing the teeth. In local treatment with nystatin, the treatments with chlorhexidine and nystatin should be at least 30 minutes apart.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Caries prophylactic agents | ||
|---|---|---|
| A01AA01 | ||
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References
- GlaxoSmithKline Consumer Health BV, SPC Corsodyl (RVG 09822), www.cbg-meb.nl, Geraadpleegd 17 aug 2011, http://db.cbg-meb.nl/IB-teksten/h09822.pdf
- Kamps WA et al, Werkboek ondersteunende behandeling in de kinderoncologie, www.nvk.nl (alleen leden), 2005
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Changes
Changes
