Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Docusate sodium/sorbitol (enema)

Generic name
Docusate sodium/sorbitol (enema)
Brand name
ATC Code
A06AG10

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Constipation
  • Rectal
    • < 6 years
      • 60 ml/dose, once only.
      • If the bowels have not been emptied after 30 minutes, 1 dose should be administered for a second time.

    • 6 years up to 18 years
      • 120 ml/dose, once only.
      • If the bowels have not been emptied after 30 minutes, 1 dose should be administered for a second time.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Abdominal pain can occur after administration; this disappears within 30 minutes.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. CBO, Richtlijn Obstipatie bij kinderen van 0-18 jaar, www.cbo.nl, 2010
  2. Bekkali NL et al, Rectal fecal impaction treatment in childhood constipation: enemas versus high doses oral PEG, Pediatrics, 2009, Dec;124(6), e1108-15
  3. Diemel JM et al, NHG-Standaard Obstipatie, Huisarts Wet, 2010, 53(9), 484-98

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Changes

Changes