Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Griseofulvin

Generic name
Griseofulvin
Brand name
ATC Code
D01BA01

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Tinea capitis
  • Oral
    • 1 month up to 18 years
      [1] [2] [3] [4]
      • 10 - 20 mg/kg/day in 1 dose
      • Duration of treatment:

        4-6 weeks

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Oestrogen-like effects (on the genitalia and breasts)

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. González U, et al, Systemic antifungal therapy for tinea capitis in children., Cochrane Database Syst Rev, 2007, 17(4), CD004685
  2. Bennet ML et al, Oral griseofulvin remains the treatment of choice for tinea capitis in children., Pediatr Dermatol, 2000, 17(4), 325-6
  3. Elewski BE et al, Terbinafine hydrochloride oral granules versus oral griseofulvin suspension in children with tinea capitis: results of two randomized, investigator-blinded, multicenter, international, controlled trials., J Am Acad Dermatol, 2008, 59(1), 41-54
  4. Kakourou T, Guidelines for the management of tinea capitis, Pediatr Dermatol, 2010, 27(3), 226-8.

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Changes

Changes