Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Gentamicin, ocular application

Generic name
Gentamicin, ocular application
Brand name
ATC Code
S01AA11

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Eye infections
  • Ocular
    • Eye drops, solution
      • 0 years up to 18 years
        [2] [3]
        • 1 drop(s)/dose 4-6x daily.
        • Duration of treatment:

          Maximum 14 days.

        • In serious cases, apply drops every 1 to 2 hours
          Use in combination with prednisolone forte after intraocular procedures.

          Treatment by or after consulting a paediatric specialist (paediatric ophthalmologist) who has experience of using gentamicin eye drops.

    • Eye salve
      • 0 years up to 18 years
        [4]
        • Insert a strand of ointment approx. 0.5 to 1 cm long (corresponds to 0.05-0.1 mg gentamicin) into the conjunctival sac of the diseased eye 2 to 3 times a day.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

The safetyprofile in children does not differ from the safetyprofile in adults. [SmPC InfectoGenta® Augensalbe]

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Risk of sensitization and crossover resistance with other aminoglycosides.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Furth van AM et al, Werkboek Infectieziekten bij Kinderen, VU Uitgeverij, 2008
  3. Ursapharm Benelux BV.. , SPC Gentamicine-POS oogdruppels (RVG 17832) 25-10-2011, www.cbg-meb.nl
  4. InfectoPharm, SmPC InfectoGenta® Augensalbe 0,3 % (6102522.00.00), 02/2014

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Changes

Changes