Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Insulin, medium long-acting and short-acting or ultrashort-acting (in combination)

Generic name
Insulin, medium long-acting and short-acting or ultrashort-acting (in combination)
Brand name
ATC Code
A10AD01

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Diabetes mellitus, insulin-dependent
  • Subcutaneous
    • 1 month up to 18 years
      • Dosage dependent on the blood sugar levels

      • Treatment by or after consulting a paediatric specialist (paediatric endocrinologist) who has experience of using insulins.

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Renal impaiment in children > 3 months

The insulin requirement may be decreased in cases of reduced renal function. The dosage is adjusted depending on the blood glucose measurements in this case.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Insulins and analogues for injection, fast-acting
A10AB01
A10AB04
Insulins and analogues for injection, intermediate-acting
A10AC01
Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
A10AD06
Insulins and analogues for injection, long-acting
A10AE

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References

  1. Novo Nordisk A/S, SmPC Novomix (EU/1/00/142/004-005) 04-02-2016, www.geneesmiddeleninformatiebank.nl
  2. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  3. Sanofi-Aventis Deutschland GmbH, SmPC Insuman Comb (EU/1/97/030/038-039) 17-05-2016, www.geneesmiddeleninformatiebank.nl
  4. Eli Lilly Nederland B.V, SmPC Humuline (RVG 14894) 01-01-2016, www.geneesmiddeleninformatiebank.nl
  5. Eli Lilly Nederland B.V, SmPC Humalog Mix (EU/1/96/007/005) 14-03-2016, www.geneesmiddeleninformatiebank.nl
  6. Novo Nordisk A/S, SmPC Mixtard (EU/1/02/231/001-002;036) 17-03-2016, www.geneesmiddeleninformatiebank.nl
  7. Novo Nordisk A/S, SPC Actraphane (EU/1/02/229/001-002;036) 12/02/2016, www.geneesmiddeleninformatiebank.nl

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Changes

Changes