Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Noscapine

Generic name
Noscapine
Brand name
ATC Code
R05DA07

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Cough
  • Oral
    • 6 months up to 3 years
      • 0.5 - 1 mg/kg/dose, as required 1-6 x daily. Max: 36 mg/day. Minimum interval between 2 doses: 4 hours.
    • 3 years up to 6 years
      • 7.5 mg/dose, as required 2-4 x daily.
    • 12 years up to 18 years
      • 15 - 30 mg/dose, as required 3-4 x daily.
      • Directions for administration:

        Swallow the tablet whole because the bitter taste of the medicine will otherwise be released.

    • 6 years up to 12 years
      • 15 mg/dose, as required 2-4 x daily.
      • Directions for administration:

        Swallow the tablet whole because the bitter taste of the medicine will otherwise be released.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Opium alkaloids and derivatives
R05DA04
R05DA09

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References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Teva BV, SmPC Noscapine (RVG 16680) 28-12-2020, www.cbg-meb.nl
  3. Vemedia Manufacturing BV, SmPC Noscapect (RVG02256) 23-05-15, www.cbg-meb.nl
  4. MMI, Online GL. Gelbe Liste Online, Accessed May 16, 2018
  5. Infectopharm, SmPC CAPVAL® Dragees 25 mg Überzogene Tabletten CAPVAL® Saft 25 mg/5 g Suspension zum Einnehmen CAPVAL® Dragees 25 mg, Saft 25 mg/5 g, Tropfen 25 mg/g (6554655.00.00, 6554632.00.00, 6554589.00.00), 01/2015
  6. DAZ.online, Individuell für Kinder, Accessed May 16, 2018
  7. Breitkreutz J, Boos J., Paediatric and geriatric drug delivery. Expert opinion on drug delivery, 2007, 4(1), 37–45

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Changes

Changes