- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Allergic rhinitis and chronic urticaria |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
In children between the ages of 2 and 12, common side effects were headache (2.7%), nervousness (2.3%), and tiredness (1%).
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Use caution in patients with severe hepatic impairment: dose adjustment:
<30 kg: 5 mg / dose every other day
>30 kg: 10mg / dose every other day (SmPC Clarityn)
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Piperazine derivatives | ||
|---|---|---|
| R06AE07 | ||
| R06AE03 | ||
| Other antihistamines for systemic use | ||
|---|---|---|
| R06AX26 | ||
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References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Schering Plought Nederland BV, SPC Claritine (RVG 13492), www.cbg-meb.nl, Geraadpleegd 4 juni 2010, http://db.cbg-meb.nl/IB-teksten/h13492.pdf
- Nederlandse Vereniging voor Dermatologie en Venereologie, Richtlijn Chronische spontane urticaria., www.ndvd.nl, 03-12-2015
- Zuberbier T, et al, , The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update., Allergy, 2014 , Jul;69(7), 868-87
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Changes
Changes
