- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The laxative effect occurs after a few hours. It may however take several days before the desired effect is achieved.
Lactitol is not absorbed or hardly absorbed in the small intestine; its effect occurs in the colon.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Constipation |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications in children
Breast-fed infants and infants with autosomal recessive hereditary fructose intolerance.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Softeners, emollients | ||
|---|---|---|
| A06AA01 | ||
| Contact laxatives | ||
|---|---|---|
| A06AB02 | ||
| A06AB08 | ||
| A06AB06 | ||
| A06AB06 | ||
| A06AB58 | ||
| Bulk-forming laxatives | ||
|---|---|---|
| A06AC01 | ||
| Osmotically acting laxatives | ||
|---|---|---|
| A06AD11 | ||
| A06AD65 | ||
| A06AD65 | ||
| A06AD15 | ||
| A06AD65 | ||
| Enemas | ||
|---|---|---|
| A06AG | ||
| A06AG10 | ||
| A06AG10 | ||
| A06AG04 | ||
| A06AG11 | ||
| A06AG01 | ||
| Other drugs for constipation | ||
|---|---|---|
| A06AX01 | ||
| A06AX02 | ||
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References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Aziende Chimiche Riunite Angelini Francesco S.p.A.. , SPC Importal 23-11-2011, www.cbg-meb.nl
- Aziende Chimiche Riunite Angelini Francesco S.p.A.., SPC Importal 23-11-2011, www.cbg-meb.nl
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Changes
Changes
