- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
Paromomycin is absorbed to a small extent.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Amoebiasis, Dientamoeba fragilis |
|---|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Tetany has been reported after intramuscular administration [Thakur 2008].
Based on the available data, the same side effect profile is expected in children and adolescents as in adults. [SmPC Humatin]
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Caution is needed in cases of renal function disorders; the possibility of accumulation cannot be excluded.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Antibiotics | ||
|---|---|---|
| A07AA02 | ||
| A07AA09 | ||
| ANTIBIOTICS | ||
|---|---|---|
| A07AA02 | ||
| A07AA09 | ||
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References
- Hartwig NC et al, Vademecum Pediatrische Antimicrobiele Therapie, 2005
- Frisari L, et al, An open, controlled study of two non-absorbable antibiotics for the oral treatment of paediatric infectious diarrhoea., Curr Med Res Opin, 1997, 14(1), 39-45
- Vandenberg O, et al, Treatment of Dientamoeba fragilis infection with paromomycin. , Pediatr Infect Dis J. , 2007 , Jan;26(1), 88-90
- Thakur CP. , Tetany in kala azar patients treated with paromomycine, Indian J Med Res, 2008, May;127(5), 489-93
- Pfizer, SmPC Humatin® Kapseln, 250 mg Hartkapseln (6419615.00.00), 11/2018
- Pfizer, SmPC Humatin® Pulvis, 1.000 mg Pulver zur Herstellung einer Lösung zum Einnehmen (40332.00.00), 11/2018
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Changes
Changes
