- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The results of pharmacokinetic studies were similar in adults and adolescents. The amount of available zolmitriptan is the same or slightly lower in adolescents compared to adults. Accordingly, the amount of the available active metabolite is slightly increased. The differences are probably not clinically not clinically significant.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Migraine: acute treatment during headache phase |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
The type and severity of side effects in children were comparable to those in adults. However, no statements can be made on the frequencies.(SmPC
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Selective serotonin (5HT1) agonists | ||
|---|---|---|
| N02CC04 | ||
| N02CC01 | ||
| Other antimigraine preparations | ||
|---|---|---|
| N02CX01 | ||
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Reference
- Grünenthal GmbH, SmPC AscoTop ® Nasal 5 mg/Dosis Nasenspray, Lösung (54619.01.00), 06/2023
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Changes
Changes
