- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The pharmacokinetics and steady-state concentrations of upadacitinib are comparable in adults and adolescents aged 12 to 17 years with atopic dermatitis [SmPC Rinvoq].
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Atopic dermatitis |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
The safety profile of upadacitinib at a dose of 15 mg/day in adolescents was similar to that in adults, although the rates of some adverse events, including neutropenia and herpes zoster, were higher in a dose-dependent manner [SmPC Rinvoq].
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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Reference
- AbbVie Deutschland GmbH & Co. KG, SmPC Rinvoq (EU/1/19/1404/009) Rev 20, www.ema.europa.eu, 24-07-2027
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Changes
Changes
