Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Fluticasone + formoterol

Generic name
Fluticasone + formoterol
Brand name
ATC Code
R03AK11

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Asthma
  • Inhalation
    • 5 years up to 12 years
      • Fluticasone propionate/formoterol fumarate 50/5 microg.: Twice daily 2 inhalations 

    • 12 years up to 18 years
      • Fluticasone propionate/formoterol fumarate 50/5 microg.: Twice daily 2 inhalations.
        If necessary, increase to 125/5 twice daily 2 inhalations.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Systemic effects, such as Cushing's syndrome, Cushing-like symptoms, adrenal suppression and growth retardation, anxiety, sleep disturbances and behavioral changes, including hyperactivity and irritability (SmPC).

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

It is recommended that growth is monitored regularly in children during long-term treatment. In case of growth retardation, reassess the treatment and reduce the dose if possible.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Alpha- and beta-adrenoreceptor agonists
R03AA01
Selective beta-2-adrenoreceptor agonists
R03AC13
R03AC02
R03AC12
R03AC03
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
R03AK08
R03AK10
R03AK07
R03AK06
Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
R03AL01
R03AL02

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Reference

  1. Mundipharma Pharmaceuticals B.V., SmPC Flutiform (RVG RVG 107222, 107242, 107243) 04-06-2021, www.geneesmiddeleninformatiebank.nl

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Changes

Changes