- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
PK data not reviewed
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Atopic dermatitis |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Prolonged use and use of high doses- especially when the skin is covered with, for example, a diaper -may lead to systemic side effects. (SmPC)
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
In infants, the diaper may act as an occlusive dressing, thereby increasing systemic absorption and leading to systemic effects. Children have a relatively large skin surface area and thin skin. Prolonged use of dermatocorticosteroids on large and damaged skin surfaces can potentially lead to more rapid systemic side effects, adrenal suppression and also growth hormone suppression in them. It is therefore recommended, when long-term application is necessary, that height and weight be monitored regularly.
When applying to the eyelids, careful consideration should be given to the possibility of contamination of the conjunctiva with the risk of developing glaucoma simplex or sub-capsular cataract on the one hand and the risk of corneal damage due to continuous rubbing of untreated exudate on the other hand.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Corticosteroids, weak (group I) | ||
|---|---|---|
| D07AA02 | ||
| Corticosteroids, potent (group III) | ||
|---|---|---|
| D07AC01 | ||
| D07AC03 | ||
| D07AC17 | ||
| D07AC13 | ||
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References
- Nederlandse Vereniging voor Dermatologie en Venerelogie, Richtlijn constitutioneel eczeem., 2019
- Nederlandse Vereniging voor Dermatologie en Venerelogie, Leidraad Dermatocorticosteroiden, 2019
- ZorgInstituut Nederland, Farmacotherapeutisch kompas (Eigenschappen, bijwerkingen, contra-indicaties, waarschuwingen en voorzorgen), Geraadpleegd 28 jun 2021
- CHEPLAPHARM Arzneimittel GmbH, SmPC Alfason® 0,1 % Creme (4932.00.00)/Salbe/Cresa/Crinale/Crelo, 03/2021
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Changes
Changes
